June 2021
Title: How does the cystic fibrosis drug ivacaftor move in the body during pregnancy and breastfeeding?
Authors Fiona Qiu, Mark D Habgood, Yifan Huang, Katarzyna M Dziegielewska, Sam Toll, Elena K Schneider-Futschik
References J Cyst Fibros. 2021 Jun 27;S1569-1993(21)01289-3. doi: 10.1016/j.jcf.2021.06.005.
Keywords Breastfeeding, Cystic fibrosis transmembrane conductance regulator, Ivacaftor, pregnancy, blood brain barrier
June 2021
Title: Use of LCI to monitor CFTR Modulator effect in people with CF
Authors Philippe Reix, Aurélie Tatopoulos, Iulia Ioan, Muriel Le Bourgeois, Stéphanie Bui, Marie Luce Choukroun, Katia Bessaci-Kabouya, Michele Gerardin, Plamen Bokov, Jennifer Da Silva, Jean-Louis Paillasseur, Pierre Regis Burgel,, French Cystic Fibrosis Reference Network study group
References J Cyst Fibros. 2021 Jun 25;S1569-1993(21)01286-8. doi: 10.1016/j.jcf.2021.06.002.
Keywords CFTR modulators, Lumacaftor, Multiple breath washout
June 2021
Title: How changes in health insurance coverage for young children with CF can impact important health outcomes, such as lung function at 6 years of age
Authors Kimberly M Dickinson, Kevin J Psoter, Kristin A Riekert, Joseph M Collaco
References J Cyst Fibros. 2021 Jun 23;S1569-1993(21)01290-X. doi: 10.1016/j.jcf.2021.06.006.
Keywords BMI, Early childhood, FEV(1)pp, health insurance, registry
Theme Care of patients with CF
June 2021
Title: Effect of elexacaftor-texacaftor-ivacaftor in cystic fibrosis patients with advanced lung disease
Authors Bermingham, B.; Rueschhoff, A. Ratti, G. Nesmith, A., Goodwin D, Gray S, Flume P, Solomon, G. M., Cohen, L., Garcia, B.
References J Cyst Fibros. 2021 Jun 21;S1569-1993(21)00160-0. doi: 10.1016/j.jcf.2021.05.009
June 2021
Title: Using an Antibiotic Treatment Called Amikacin Liposome Inhalation Suspension (or ALIS) for Chronic Infection With Pseudomonas aeruginosa in People With Cystic Fibrosis for 2 years
Authors Diana Bilton, Isabelle Fajac, Tacjana Pressler, John Paul Clancy, Dorota Sands, Predrag Minic, Marco Cipolli, Ivanka Galeva, Amparo Solé, Alexandra L Quittner, Zhanna Jumadilova, Monika Ciesielska, Michael W Konstan, CLEAR-110 Study Group
References J Cyst Fibros. 2021 Jun 15;S1569-1993(21)00164-8. doi: 10.1016/j.jcf.2021.05.013.
Keywords ALIS, Amikacin, Liposomal, Pseudomonas aeruginosa
June 2021
Title: Complications relating to the heart and blood vessels in people with Cystic Fibrosis: A Review of the Literature
Authors T. Spencer Poore, Jennifer Taylor-Cousar, Edith Zemanick
References J Cyst Fibros. 2021 Jun 14;S1569-1993(21)00126-0. doi: 10.1016/j.jcf.2021.04.016.
Keywords CFTR, Cardiovascular disease, sildenafil
June 2021
Title: Cystic fibrosis-related diabetes (CFRD) and cognitive ability (memory, attention and task switching) in adults with cystic fibrosis
Authors Helen K Chadwick, Janice Abbott, Margaret Anne Hurley, Louise Dye, Clare L Lawton, Michael W Mansfield, Daniel Peckham
References J Cyst Fibros. 2021 Jun 13;S1569-1993(21)00124-7. doi: 10.1016/j.jcf.2021.04.014.
Keywords Cognition, Cognitive tests, Cystic fibrosis-related diabetes, Executive function
Title: Liver toxicity with triple therapy in cystic fibrosis: when it is worth taking the risk.
Authors Dimitri Stylemans, Silke François, Stefanie Vincken, Sylvia Verbanck, Eef Vanderhelst
References J Cyst Fibros. 2021 Jun 13;S1569-1993(21)00174-0. doi: 10.1016/j.jcf.2021.05.017.
June 2021
Title: New drug for cystic fibrosis does not significantly interfere with another drug that prevents organ rejection
Authors Megan Smith, Kevin J Ryan, Hector Gutierrez, Luz Helena Gutierrez Sanchez, Janaina Nogueira Anderson, Edward P Acosta, Kim W Benner, Jennifer S Guimbellot
References J Cyst Fibros. 2021 Jun 12;S1569-1993(21)00159-4. doi: 10.1016/j.jcf.2021.05.008.
Keywords CFTR, Cytochrome p450, Drug interaction, Elexacaftor, Ivacaftor, Liver transplantation, Tacrolimus, Tezacaftor
June 2021
Title: What do different bacteria together do to the lung epithelium in Cystic Fibrosis
Authors Bertelsen, J Stuart Elborn, Bettina C Schock
References J Cyst Fibros. 2021 Jun 7;S1569-1993(21)00122-3. doi: 10.1016/j.jcf.2021.04.012.
Keywords Airway microbiome, Anaerobic bacteria, Cystic Fibrosis Airways inflammation, Host-pathogen-interaction, Mixed infection, Prevotella spp., Signalling
June 2021
Title: Comparison of gene editing methods to correct the W1282X mutation
Authors Lúcia Santos, Karen Mention, Kader Cavusoglu-Doran, David J Sanz, Mafalda Bacalhau, Miquéias Lopes-Pacheco, Patrick T Harrison, Carlos M Farinha
References J Cyst Fibros. 2021 Jun 5;S1569-1993(21)00167-3. doi: 10.1016/j.jcf.2021.05.014.
Keywords CFTR, CRISPR/Cas12a, CRISPR/Cas9, human bronchial epithelial cells, W1282X
Title: Appearance and behaviour of methicillin resistant Staphylococcus aureus (MRSA) from early and chronic infection in cystic fibrosis (CF)
Authors Deirdre Gilpin, Lucas R Hoffman, Agathe Ceppe, Marianne S Muhlebach
References J Cyst Fibros. 2021 Jun 5;S1569-1993(21)00168-5. doi: 10.1016/j.jcf.2021.05.015.
Keywords Adaptation, Anaerobe, Antimicrobial resistance, Haemolysis, Outcome, Staphylococcus aureus
June 2021
Title: Effect of inhaled antibiotic therapy with levofloxacin in people with cystic fibrosis
Authors Carsten Schwarz, Claudia Grehn, Svenja Temming, Frederik Holz, Patience Ndidi Eschenhagen
References J Cyst Fibros. 2021 Jun 4;S1569-1993(21)00051-5. doi: 10.1016/j.jcf.2021.03.002.
Keywords chronic Pseudomonas aeruginosa infection, Inhaled antibiotics, Levofloxacin solution, Pulmonary function test, exacerbation rate
June 2021
Title: Can a new blood test be used to screen for CF-related diabetes ?
Authors Tom Toin, Quitterie Reynaud, Angélique Denis, Isabelle Durieu, Catherine Mainguy, Catherine Llerena, Isabelle Pin, Sandrine Touzet, Philippe Reix
References J Cyst Fibros. 2021 Jun 2;S1569-1993(21)00161-2. doi: 10.1016/j.jcf.2021.05.010.
Keywords CFRD, Diabetes, HOMA, Homeostasis, Indice
Title: Evaluating Pulmonary Exacerbation Treatment Differences in Women and Men with CF
Authors Kristina Montemayor, Kevin J Psoter, Noah Lechtzin, Sara W Carson, Christian A Merlo, Rebecca H Dezube, Kristin A Riekert, Sarah Allgood, Alexandra Toporek, Mark T Jennings, Natalie E West
References J Cyst Fibros. 2021 Jun 2;S1569-1993(21)00163-6. doi: 10.1016/j.jcf.2021.05.012.
Keywords Pulmonary exacerbations, Sex differences, Treatment patterns
June 2021
Title: Respiratory symptoms are not more frequent or severe in infants with CF compared to healthy infants.
Authors Insa Korten, Marc-Alexander Oestreich, Urs Frey, Alexander Moeller, Andreas Jung, Renate Spinas, Dominik Mueller-Suter, Daniel Trachsel, Isabelle Rochat, Ben Spycher, Philipp Latzin, Carmen Casaulta, Kathryn Ramsey
References J Cyst Fibros. 2021 Jun 1;S1569-1993(21)00116-8. doi: 10.1016/j.jcf.2021.04.006.
Keywords Cohort study, Healthy controls, Infancy, Respiratory symptoms
