CF Research News for August 2020 | European Cystic Fibrosis Society (ECFS)

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With the CF Research News, we aim to bridge the gap between people with CF and the researchers investigating CF and how best to treat those with the condition.
We want to provide access to patients, parents, relatives, friends and caregivers of patients with CF to all scientific work mainly published in the Journal of Cystic Fibrosis (JCF).

All PDF files published hereunder are lay version summaries of work published in the JCF.

August 2020

Title: Immune response of polarized cystic fibrosis airway epithelial cells infected with Influenza A virus

Authors

Aderonke Sofoluwe, Alice Zoso, Marc Bacchetta, Sylvain Lemeille, Marc Chanson

References

J Cyst Fibros. 2020 Aug 29;S1569-1993(20)30827-4. doi: 10.1016/j.jcf.2020.08.012. Online ahead of print.

Keywords

Airway epithelium, Immune response, Pathogens, Transcriptome

CF Research News Article

Scientific Abstract

August 2020

Title: Recommended shielding against COVID-19 impacts physical activity levels in adults with cystic fibrosis

Authors

Thomas Radtke, Sarah R Haile, Holger Dressel, Christian Benden

References

J Cyst Fibros. 2020 Aug 28;S1569-1993(20)30828-6. doi: 10.1016/j.jcf.2020.08.013

Keywords

COVID-19, Coronavirus, Lung disease, Lung transplantation, SARS-CoV-2

CF Research News Article

Scientific Abstract

August 2020

Title: Extensive CFTR sequencing through NGS in Brazilian individuals with cystic fibrosis: unravelling regional discrepancies in the country

Authors

Luiz Vicente Ribeiro Ferreira da Silva Filho, Paulo José Cauduro Maróstica, Rodrigo Abensur Athanazio, Francisco José Caldeira Reis, Neiva Damaceno, Angela Tavares Paes, Adilson Yuuji Hira, David Schlesinger, Fernando Kok, Margarida D Amaral, Brazilian Cystic Fibrosis Patient Registry Contributors Team

References

J Cyst Fibros. 2020 Aug 17;S1569-1993(20)30822-5. doi: 10.1016/j.jcf.2020.08.007.

Keywords

Brazil, Diagnosis, Genetics, Newborn screening, sweat chloride

CF Research News Article

Scientific Abstract

August 2020

Title: The implementation of an aminoglycoside induced ototoxicity algorithm for people with cystic fibrosis

Authors

E. Claire Elson, Ellen Meier, Christopher M. Oermann

References

J Cyst Fibros. 2020 Aug 15;S1569-1993(20)30817-1. doi: 10.1016/j.jcf.2020.08.002. Online ahead of print.

Keywords

Aminoglycoside, Ototoxicity

CF Research News Article

Scientific Abstract

August 2020

Title: Long-term safety study of colistimethate sodium (Colobreathe®): Findings from the UK Cystic Fibrosis Registry

Authors

Sigal Kaplan, Andrew Lee, Noreen Caine, Susan C Charman, Diana Bilton

References

J Cyst Fibros. 2020 Aug 14;S1569-1993(20)30816-X. doi: 10.1016/j.jcf.2020.08.001. Online ahead of print.

Keywords

Colistimethate sodium dry powder for inhalation, Colobreathe, Long-term safety, UK Cystic Fibrosis Registry

CF Research News Article

Scientific Abstract

August 2020

Title: Changes in symptom scores as a potential clinical endpoint for studies of cystic fibrosis pulmonary exacerbation treatment

Authors

D R VanDevanter, S L Heltshe, D B Sanders, N E West, M Skalland5, P A Flume, C H Goss, STOP-OB Study

References

J Cyst Fibros. 2020 Aug 13;S1569-1993(20)30820-1. doi: 10.1016/j.jcf.2020.08.006. Online ahead of print.

Keywords

clinical trials, Exacerbations, Symptoms

CF Research News Article

Scientific Abstract

August 2020

Title: Decreased survival in cystic fibrosis patients with a positive screen for depression

Authors

Michael S Schechter, Joshua S Ostrenga, Aliza K Fink, David H Barker, Gregory S Sawicki, Alexandra L Quittner

References

J Cyst Fibros. 2020 Aug 12;S1569-1993(20)30812-2. doi: 10.1016/j.jcf.2020.07.020.

Keywords

anxiety, depression, mental health, mortality

CF Research News Article

Scientific Abstract

August 2020

Title: SARS-CoV-2 seroprevalence in a Belgian cohort of patients with cystic fibrosis

Authors

Berardis S, Verroken A, Vetillart A, Struyf C, Gilbert M, Gruson D, Gohy S

References

J Cyst Fibros. 2020 Aug 11;S1569-1993(20)30821-3. doi: 10.1016/j.jcf.2020.08.005

Keywords

COVID-19, SARS-CoV-2, Seroprevalence

CF Research News Article

Scientific Abstract

August 2020

Title: Screening for Nontuberculous mycobacteria (NTM) in people with Cystic Fibrosis

Authors

Jerry A. Nick, Prithwiraj De, Delphi Chatterjee

References

J Cyst Fibros. 2020 Aug; 9

CF Research News Article

Scientific Abstract

August 2020

Title: Projecting the impact of delayed access to elexacaftor/tezacaftor/ivacaftor for people with Cystic Fibrosis

Authors

Sanja Stanojevic, Katarina Vukovojac, Jenna Sykes, Felix Ratjen, Elizabeth Tullis, Anne L Stephenson

References

J Cyst Fibros. 2020 Aug 5;S1569-1993(20)30809-2. doi: 10.1016/j.jcf.2020.07.017. Online ahead of print.

Keywords

forecasting, Microsimulation, Modulators

CF Research News Article

Scientific Abstract

August 2020

Title: Azithromycin and Tezacaftor/Ivacaftor is associated with first-degree heart block in an adult with Cystic Fibrosis

Authors

Yang Song, Alexandra Coronel Palacios, Aravinda Thiagalingam, Peter G Middleton

References

J Cyst Fibros. 2020 Aug 4;S1569-1993(20)30808-0. doi: 10.1016/j.jcf.2020.07.016. Online ahead of print.

Keywords

Azithromycin, First degree heart block, Ivacaftor, Tezacaftor

CF Research News Article

Scientific Abstract

August 2020

Title: Heat acclimation improves sweat gland function and lowers sweat sodium concentration in an adult with cystic fibrosis

Authors

Ashley G B Willmott, Robert Holliss, Zoe Saynor, Jo Corbett, Adam J Causer, Neil S Maxwell

References

J Cyst Fibros. 2020 Aug 2;S1569-1993(20)30804-3. doi: 10.1016/j.jcf.2020.07.013.

Keywords

Adaptation, Heat acclimation, Heat stress, Sweat sodium concentration

CF Research News Article

Scientific Abstract