With the CF Research News, we aim to bridge the gap between people with CF and the researchers investigating CF and how best to treat those with the condition.
We want to provide access to patients, parents, relatives, friends and caregivers of patients with CF to all scientific work mainly published in the Journal of Cystic Fibrosis (JCF).

All PDF files published hereunder are lay version summaries of work published in the JCF.

October 2022

Title: Best therapeutic approaches to treat everyone with CF
Authors
Margarida D Amaral, Patrick T Harrison
References
J Cyst Fibros. 2022 Oct 30;S1569-1993(22)01389-3. doi: 10.1016/j.jcf.2022.10.007.
Keywords
CFTR, Genome editing, Theratypes
Theme
CFTR/Basic Science
PDF icon CF Research News Article
Scientific Abstract

October 2022

Title: Gastrointestinal symptom burden in cystic fibrosis
Authors
Baha Moshiree, A Jay Freeman, Phuong T Vu, Umer Khan, Carmen Ufret-Vincenty, Sonya L Heltshe, Christopher H Goss, Sarah Jane Schwarzenberg, Steven D Freedman, Drucy Borowitz, Meghana Sathe, GALAXY Study Group
References
J Cyst Fibros. 2022 Oct 29;S1569-1993(22)01388-1. doi: 10.1016/j.jcf.2022.10.006.
 
Keywords
Constipation, Gastrointestinal questionnaires, Gastrointestinal symptoms, Patient-reported outcome measures
Theme
Care of patients with CF, Nutrition/Gastroenterology
PDF icon CF Research News Article
Scientific Abstract

October 2022

Title: Effect of ETI on CF Gastrointestinal Disease
Authors
Sarah Jane Schwarzenberg, Phuong T Vu, Michelle Skalland, Lucas R Hoffman, Christopher Pope, Daniel Gelfond, Michael R Narkewicz, David P Nichols, Sonya L Heltshe, Scott H Donaldson, Carla A Frederick, Andrea Kelly, Jessica E Pittman, Felix Ratjen,, Margaret Rosenfeld, Scott D Sagel, George M Solomon, Michael S Stalvey, John P Clancy, Steven M Rowe, Steven D Freedman, Promise Study Group
References
J Cyst Fibros. 2022 Oct 21;S1569-1993(22)01384-4. doi: 10.1016/j.jcf.2022.10.003.
Keywords
Inflammation, Modulators, pancreatic insufficiency, Patient-reported outcomes measures
Theme
Care of patients with CF, Nutrition/Gastroenterology
PDF icon JCF-D-22-00162R1_FINAL_Doumit_301022.pdf
Scientific Abstract

October 2022

Title: The risk of developing bowel cancer in people with cystic fibrosis, or cystic fibrosis causing mutations.
Authors
Rebecca J. Birch, Daniel Peckham, Henry M. Wood, Philip Quirke, Rob Konstant-Hambling, Keith Brownlee, Rebecca Cosgriff, Genomics England Research Consortium, Nicholas Burr, Amy Downing
References
J Cyst Fibros. 2022 Oct 14;S1569-1993(22)01383-2. doi: 10.1016/j.jcf.2022.10.001.
Theme
Care of patients with CF
PDF icon CF Research News Article
Scientific Abstract

October 2022

Title: New guidelines on non CF disorders related to the CFTR gene
Authors
Castellani C, De Boeck K, De Wachter E, Sermet-Gaudelus I, Simmonds NJ, Southern KW, on behalf of the ECFS Diagnostic Network Working Group
References
J Cyst Fibros. 2022 Oct 8;S1569-1993(22)00691-9. doi: 10.1016/j.jcf.2022.09.011.
Keywords
CFTR, CFTR biomarkers, CFTR related disorders, CFTR sequence variations, Follow-up, Intestinal current measurement, Nasal potential difference, Sweat test, treatment
Theme
Diagnosis/Screening
PDF icon CF Research News Article
Scientific Abstract