With the CF Research News, we aim to bridge the gap between people with CF and the researchers investigating CF and how best to treat those with the condition.
We want to provide access to patients, parents, relatives, friends and caregivers of patients with CF to all scientific work mainly published in the Journal of Cystic Fibrosis (JCF).

All PDF files published hereunder are lay version summaries of work published in the JCF.

May 2025

Title: Can exercise replace airway clearance (chest physiotherapy) in the era of CFTR modulator medications – summary of a Pro/Con debate
Authors
G. Stanford, K. von Berg, C. Smith, M. Richmond, J. Walzel, L. Morrison
References
J Cyst Fibros. 2025 May 16:S1569-1993(25)01468-7.  doi: 10.1016/j.jcf.2025.05.001
Keywords
airway clearance, Exercise, Physical therapy, physiotherapy, Respiratory therapy
File JCF-D-25-00067R1_FINAL_Stanford_270725.docx
Title: From Clinical Trials to Real Life: Impact of Elexacaftor/Tezacaftor/Ivacaftor in the United Kingdom
Authors
Gabriela Vega-Hernandez, Gordon MacGregor, Andrew Wilfin, Francis Adams, Ciarán Haugh, Carl A. Baxter, Heike Wöhling, Sarah L. Clarke, Susan C. Charman, Siobhán B. Carr
References
J Cyst Fibros. 2025 May 15:S1569-1993(25)01467-5.  doi: 10.1016/j.jcf.2025.04.012
Keywords
Cystic fibrosis, Elexacaftor, Ivacaftor, Real-world, registry, Tezacaftor
File JCF-D-24-00481R3_FINAL_Vega-Hernandez_200725.docx
Title: Understanding Changes in Physical Health and Care of People with CF on Modulator Therapy
Authors
Cynthia D. Brown, Carla Frederick, Elizabeth Yu , Emily Zagnit , Joel R. King, Aricca D. Van Citters
References
J Cyst Fibros. 2025 May 3:S1569-1993(25)01465-1. doi: 10.1016/j.jcf.2025.04.010
Keywords
CFTR modulator therapies, Cystic fibrosis, Experience of care, Physical well-being
File JCF-D-24-00549R1_FINAL_Brown_080625.docx
Title: Studying How Medicare and Medicaid Are Paying for CFTR Modulators Over Time
Authors
Wanjae Cho, Michael D. Parkins, Christina S. Thornton, Stephen E. Congly
References
J Cyst Fibros. 2025 May 5:S1569-1993(25)01463-8. doi: 10.1016/j.jcf.2025.04.008
Keywords
CFTR modulator, Health economics, Medications, policy
File JCF-D-24-00565R2_FINAL_Congly_080625.docx
Title: Anti-inflammatory Treatment for Exacerbations in Cystic Fibrosis
Authors
Natalie E. West, Michael W. Konstan, Patrick A. Flume, Donald R. VanDevanter, Amalia Magaret, Henryk Mazurek, Elena L. Amelina, István Laki, Raphael Chiron, Sivagurunathan Suthersan, Carla Columbo, Henry L. Dorkin, Damian G. Downey, Amparo Sole, Lena Hjelte, Elizabeth Tullis, Nancy Dgetluck, Quinn Dinh, Scott Constantine, Barbara White, J. Stuart Elborn,* James F. Chmiel;* for the JBT101-CF-002 Study Group
References
J Cyst Fibros. 2025 May 26:S1569-1993(25)00111-0. doi: 10.1016/j.jcf.2025.03.015.
Keywords
Cystic fibrosis, Lenabasum, Pulmonary exacerbations, Safety
Theme
Care of patients with CF
PDF icon JCF-D-24-00160R1_FINAL_West_230425.pdf
Original manuscript citation in PubMed - NA 23rd April 2025