With the CF Research News, we aim to bridge the gap between people with CF and the researchers investigating CF and how best to treat those with the condition.
We want to provide access to patients, parents, relatives, friends and caregivers of patients with CF to all scientific work mainly published in the Journal of Cystic Fibrosis (JCF).

All PDF files published hereunder are lay version summaries of work published in the JCF.

February 2023

Title: Investigating the diagnostic potential of small cell particles in the blood of people with CF
Authors
Anne Trappe, Navya Lakkappa, Suzanne Carter, Eugene Dillon, Kieran Wynne, Edward McKone, Paul McNally, Judith A Coppinger
References
J Cyst Fibros. 2023 Feb 27;S1569-1993(23)00056-5. doi: 10.1016/j.jcf.2023.02.005.
Keywords
Extracellular vesicles, Inflammation, Serum
Theme
CFTR/Basic Science
PDF icon CF Research News Article
Scientific Abstract
Title: More favorable growth profiles in early childhood are associated with higher lung function at age six
Authors
Kevin J Psoter, Kimberly M Dickinson, Kristin A Riekert, Joseph M Collaco
References
J Cyst Fibros. 2023 Feb 27;S1569-1993(23)00060-7. doi: 10.1016/j.jcf.2023.02.008.
Keywords
BMI, Early childhood, FEV(1)pp, Growth trajectories, registry, WFL
Theme
Care of patients with CF, Nutrition/Gastroenterology
PDF icon CF Research News Article
Scientific Abstract

February 2023

Title: Suicide Attempts in Adolescents with Cystic Fibrosis on Elexacaftor/Tezacaftor/Ivacaftor Therapy
Authors
Meliksah Arslan, Sarah Chalmers, Kelly Rentfrow, Janelle M Olson, Vicki Dean, Mark E Wylam, Nadir Demirel
References
J Cyst Fibros. 2023 Feb 7;S1569-1993(23)00023-1. doi: 10.1016/j.jcf.2023.01.015.
Keywords
Adolescent, Covid-19 pandemic, depression, Elexacaftor/tezacaftor/ivacaftor, Mental adverse effects, mental health, Suicide
Theme
Care of patients with CF, Psychosocial
PDF icon CF Research News Article
Scientific Abstract

February 2023

Title: CFTR modulators: a new therapeutic approach but not for all CF patients
Authors
Carla Colombo, Grant A Ramm, Anders Lindblad, Fabiola Corti, Luigi Porcaro, Federico Alghisi, Irina Asherova, Helen Evans, Nataliya Kashirskaya, Elena Kondratyeva, Peter J Lewindon, Isabelle de Monestrol, Mark Oliver, Chee Y Ooi, Rita Padoan, Sahana Shank
References
J Cyst Fibros. 2023 Feb 2;S1569-1993(23)00020-6. doi: 10.1016/j.jcf.2023.01.012.
Keywords
CFTR genotype, CFTR modulators, Cirrhosis, liver disease, portal hypertension
Theme
Care of patients with CF, Nutrition/Gastroenterology
PDF icon CF Research News Article
Scientific Abstract