With the CF Research News, we aim to bridge the gap between people with CF and the researchers investigating CF and how best to treat those with the condition.
We want to provide access to patients, parents, relatives, friends and caregivers of patients with CF to all scientific work mainly published in the Journal of Cystic Fibrosis (JCF).

All PDF files published hereunder are lay version summaries of work published in the JCF.

February 2024

Title: Remote endpoints for research in cystic fibrosis
Authors
Jordana E Hoppe, Jacquelyn Sjoberg, Gina Hong, Katie Poch, Edith T Zemanick, Stephanie Thee, Claire Edmondson, Dhiren Patel, Meghana Sathe, Drucy Borowitz, Melissa S Putman, Noah Lechtzin, Kristin A Riekert, Melissa Basile, Christopher H Goss,, Mary Elizabeth Jarosz, Margaret Rosenfeld Clinical trials, Home, Remote monitoring.
References
J Cyst Fibros. 2024 Feb 29:S1569-1993(24)00023-7. doi: 10.1016/j.jcf.2024.02.011.
Keywords
clinical trials, Home, Remote monitoring
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Scientific Abstract

February 2024

Title: Repurposing enzymes to degrade complex biofilms containing two bacteria and improve antibiotic activity
Authors
Zhifen Wang, Rita Vanbever, Joseph H Lorent, Jessica Solis, Christiane Knoop, Françoise Van Bambeke
References
J Cyst Fibros. 2024 Feb 23:S1569-1993(24)00027-4. doi: 10.1016/j.jcf.2024.02.012.
Keywords
Alginate lyase, Artificial sputum medium, DNase I, Dual-species biofilm, Meropenem, Tobramycin, Pseudomonas aeruginosa, Staphylococcus aureus
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Scientific Abstract

February 2024

Title: A review of medications and medical devices used for preventing pregnancy in people with cystic fibrosis
Authors
E. Claire Elson, Taylor Imburgia, Kevin Lonabaugh, Lindsey McCoy, Nicole E. Omecene, Shannon M. Rotolo
References
NA 21 February 2024
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February 2024

Title: Amount of chloride in the sweat of people with CF taking CFTR modulators
Authors
ET Zemanick, I Emerman, M McCreary, N Mayer-Hamblett, MN Warden, K Odem-Davis, DR VanDevanter, CL Ren, J Young, MW Konstan for the CHEC-SC Study Group
References
J Cyst Fibros. 2024 Feb 14:S1569-1993(24)00015-8. doi: 10.1016/j.jcf.2024.02.001.
Keywords
CFTR function, CFTR modulators, Epidemiology, sweat chloride
PDF icon JCF-D-23-00402R1_FINAL_Zemanick_300324.pdf
Scientific Abstract
Title: Use of inhaled antibiotics to treat Pseudomonas aeruginosa infections in Europe.
Authors
Callum M. Sloan, Laura J. Sherrard, Gisli G. Einarsson, Lieven J. Dupont, Silke van Koningsbruggen-Rietschel, Nicholas J. Simmonds, Damian G. Downey
References

J Cyst Fibros. 2024 Feb 14:S1569-1993(23)01683-1. doi: 10.1016/j.jcf.2023.11.012.

Keywords
Inhaled antibiotics, Pseudomonas aeruginosa
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Scientific Abstract

February 2024

Title: Effect of stopping inhaled therapies on mucus clearance while on elexacaftor/tezacaftor/ivacaftor
Authors
Scott H Donaldson, Timothy E Corcoran, Joseph M Pilewski, Beth L Laube, Peter Mogayzel, Agathe Ceppe, Jihong Wu, Kirby Zeman, Steven M Rowe, David P Nichols, Alex H Gifford, William D Bennett, Nicole Mayer-Hamblett; SIMPLIFY MCC Study teams
References
J Cyst Fibros. 2024 Feb 13:S1569-1993(24)00018-3. doi: 10.1016/j.jcf.2024.02.003
Keywords
Clinical trial, Dornase alfa, Hypertonic saline, Mucociliary clearance, Withdrawal
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Scientific Abstract

February 2024

Title: Nationwide records suggest some people with CF have improved digestion with ivacaftor
Authors
Rebecca Calthorpe, Margaret Rosenfeld, Christopher H. Goss, Nicole Green, Mark Derleth, Siobhán B Carr, Alan Smyth, Iain Stewart
References
J Cyst Fibros. 2024 Feb 10:S1569-1993(24)00012-2. doi: 10.1016/j.jcf.2024.01.011
Keywords
Gastrointestinal, Ivacaftor, PERT, pancreas, Prevalence, registry
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Scientific Abstract