With the CF Research News, we aim to bridge the gap between people with CF and the researchers investigating CF and how best to treat those with the condition.
We want to provide access to patients, parents, relatives, friends and caregivers of patients with CF to all scientific work mainly published in the Journal of Cystic Fibrosis (JCF).

All PDF files published hereunder are lay version summaries of work published in the JCF.

March 2024

Title: Analysis of cell mechanisms influencing Covid-19 disease in cystic fibrosis patients and in the general population
Authors
Fabiana Ciciriello, Francesco Panariello, Paola Medino, Arianna Biffi, Federico Alghisi, Chiara Rosazza, Patrizia Annunziata, Valentina Bouchè, Antonio Grimaldi, Daniela Guidone, Arianna Venturini, Gianfranco Alicandro, Massimo Oggioni, Pellegrino Cerino,, Giulia Paiola, Andrea Gramegna, Alessandro Fiocchi, Alessandra Bandera, Vincenzina Lucidi, Davide Cacchiarelli, Luis J V Galietta, Carla Colombo
References
J Cyst Fibros. 2024 Mar 19:S1569-1993(24)00036-5. doi: 10.1016/j.jcf.2024.03.006.
Keywords
COVID-19, Gene expression, RNA sequencing, SARS-CoV-2, Virus-host interactions
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Scientific Abstract

March 2024

Title: Correlation between trough concentration and exposure during the day for elexacaftor, tezacaftor and ivacaftor
Authors
Steffie E M Vonk, Josje Altenburg, Ron A A Mathôt, E Marleen Kemper; Amsterdam Mucociliary Clearance Disease (AMCD) Research Group
References
J Cyst Fibros. 2024 Mar 16:S1569-1993(24)00038-9. doi: 10.1016/j.jcf.2024.03.010.
Keywords
Area under the curve, CFTR modulators, Elexacaftor-tezacaftor-ivacaftor, Therapeutic drug monitoring, Trough concentration
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Scientific Abstract

March 2024

Title: Education, employment, and income among people living with cystic fibrosis across three decades
Authors
Camilla Bjørn Jensen, Kristoffer Jarlov Jensen, Tacjana Pressler, Terese L Katzenstein, Marianne Skov, Tavs Qvist, Mette Frahm Olsen, Majbritt Jeppesen, Søren Jensen-Fangel, Hanne Vebert Olesen, Simon Bertram Reuter, Hans Kristian Råket Pedersen,, Joanna Nan Wang, Steven Michalopoulos, Lisa McGarry, Heike Wöhling, Janne Petersen, Espen Jimenez-Solem; TransformCF study group
References
J Cyst Fibros. 2024 Mar 14:S1569-1993(24)00039-0. doi: 10.1016/j.jcf.2024.03.009.
Keywords
Education, Employment, Income
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Scientific Abstract
Title: Impact of modulator therapy on iron deficiency in cystic fibrosis
Authors
Shijing Jia, Yizhuo Wang, Melissa H Ross, Jonathan B Zuckerman, Susan Murray, MeiLan K Han, Shannon E Cahalan, Blair E Lenhan, Ryan N Best, Jennifer L Taylor-Cousar, Richard H Simon, Linda J Fitzgerald, Jonathan P Troost, Suman L Sood, Alex H Gifford
References
J Cyst Fibros. 2024 Mar 14:S1569-1993(24)00030-4. doi: 10.1016/j.jcf.2024.03.002.
Keywords
anemia, CFTR modulator therapies, Iron deficiency, Nutrition
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Scientific Abstract

March 2024

Title: Use of health care before lung transplantation or death in people with cystic fibrosis
Authors
Erika Guyot, Quitterie Reynaud, Manon Belhassen, Marjorie Bérard, Clémence Dehillotte, Lydie Lemonnier, Marie Viprey, Eric Van Ganse, Pierre-Régis Burgel, Isabelle Durieu
References
J Cyst Fibros. 2024 Mar 12:S1569-1993(24)00031-6. doi: 10.1016/j.jcf.2024.03.001
Keywords
Claims data, Costs, Healthcare resource utilization, National registry, transplantation
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Scientific Abstract

March 2024

Title: What symptoms are most common and most bothersome for people living with cystic fibrosis?
Authors
Natalia Smirnova, Jane Lowers, Alexandre Cammarata-Mouchtouris, Elisabeth P Dellon, Anne Fitzpatrick, Dio Kavalieratos
References
J Cyst Fibros. 2024 Mar 8:S1569-1993(24)00033-X. doi: 10.1016/j.jcf.2024.03.005.
Keywords
Palliative care, Quality of life, Symptom management
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Scientific Abstract

March 2024

Title: CFTR modulators in people with CF and the I1234V mutation
Authors
Bat El Bar Aluma, Joel Reiter, Ori Efrati, Yael Bezalel, Shlomit Keler, Moshe Ashkenazi, Adi Dagan, Yael Buchnik, Ido Sadras, Malena Cohen-Cymberknoh
References
J Cyst Fibros. 2024 Mar 4:S1569-1993(24)00019-5. doi: 10.1016/j.jcf.2024.02.008.
Keywords
CFTR modulators, Elexacaftor/tezacaftor/ivacaftor, I1234V CFTR mutation
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Scientific Abstract

March 2024

Title: 2023 Year in Review Literature Review
Authors
Luca Cristiani, Flávia Fonseca Fernandes
References
J Cyst Fibros. 2024 Mar 1:S1569-1993(24)00022-5. doi: 10.1016/j.jcf.2024.02.007.
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Scientific Abstract