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With the CF Research News, we aim to bridge the gap between people with CF and the researchers investigating CF and how best to treat those with the condition.
We want to provide access to patients, parents, relatives, friends and caregivers of patients with CF to all scientific work mainly published in the Journal of Cystic Fibrosis (JCF).

All PDF files published hereunder are lay version summaries of work published in the JCF.

January 2025

Title: Tracking the effects of ETI treatment on pancreas in an infant over 1.7 years using stool tests
Authors
Dorothea Appelt, Teresa Fuchs, Johannes Eder, Katharina Niedermayr, Anja Siedl, Helmut Ellemunter
References
J Cyst Fibros. 2025 Jan 28:S1569-1993(25)00012-8. doi: 10.1016/j.jcf.2025.01.012
Keywords
ETI, Pancreatic sufficiency, Faecal elastase, pancreatic insufficiency
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Scientific Abstract
Title: Male Sexual and Reproductive Health in Cystic Fibrosis: A Concept Mapping Study
Authors
Kelly A Prangley, Olivia M Stransky, Jessica G Burke, Sigrid L Ladores, Kara S Hughan, Gregory S Sawicki, Traci M Kazmerski
References
J Cyst Fibros. 2025 Jan 28:S1569-1993(25)00011-6. doi: 10.1016/j.jcf.2025.01.011.
Keywords
Concept mapping, Sexual and reproductive health
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Scientific Abstract

January 2025

Title: Pain in adults with cystic fibrosis – are we painfully unaware?
Authors
Anastasia Ward, Ramil Mauleon, Gretel Davidson, Chee Y Ooi, Nedeljka Rosić
References
J Cyst Fibros. 2025 Jan 25:S1569-1993(25)00009-8. doi: 10.1016/j.jcf.2025.01.009.
Keywords
Burden of disease, CFTR, Measurement, Online survey, Prevalence of pain, Symptom perception
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Scientific Abstract

January 2025

Title: Changes in eye development in baby rats exposed to ETI when in the womb
Authors
Yimin Zhu, Mengliang Wu, Danni Li, Mark Habgood, Holly R Chinnery, Elena K Schneider-Futschik
References
J Cyst Fibros. 2025 Jan;24(1):21-25. doi: 10.1016/j.jcf.2024.11.014. Epub 2024 Dec 5
Keywords
ETI, Eye development, Ocular development, pregnancy, Trikafta
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Scientific Abstract

January 2025

Title: Kaftrio® quickly modifies the composition of breath in children with CF.
Authors
Emmanuelle Bardin, Nicolas Hunzinger, Elodie Lamy, Camille Roquencourt, Bingqing Zhou, Yasmine Tabache, Laurence Le Clainche, Natascha Remus, Charlotte Roy, Philippe Devillier, Thao Nguyen-Khoa, Frédérique Chedevergne, Clément Pontoizeau, Mairead Kelly,, Stanislas Grassin Delyle, Isabelle Sermet-Gaudelus
References
J Cyst Fibros. 2025 Jan 21:S1569-1993(25)00004-9. doi: 10.1016/j.jcf.2025.01.004.
Keywords
CFTR modulators, Lung function, Volatile organic compounds, Biomarkers, breathomics
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Scientific Abstract

January 2025

Title: Racial Disparities in Lung Transplantation for People with Cystic
Authors
Jessica M Ruck, Shi Nan Feng, Alexandra H Toporek, Pali D Shah, Erin Tallarico, Noah Lechtzin, Allan B Massie, Dorry L Segev, Errol L Bush, Christian A Merlo
References
J Cyst Fibros. 2025 Jan 16:S1569-1993(25)00008-6. doi: 10.1016/j.jcf.2025.01.006.
Keywords
Epidemiology, Highly effective modulator therapy, Lung transplantation, Race
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Scientific Abstract

January 2025

Title: Improvements in tummy and bowel symptoms after short and longer term Elexacaftor / Tezacaftor / Ivacaftor therapy (ETI)
Authors
L.R. Caley , L. Gillgrass , C. Zagoya, H. Saumtally, F. Duckstein, H. White, J.G. Mainz, D.G. Peckham
References
J Cyst Fibros. 2025 Jan 14:S1569-1993(25)00010-4. doi: 10.1016/j.jcf.2025.01.010.
Keywords
CFAbd-Score, Elexacaftor/tezacaftor/ivacaftor (ETI) therapy, Gastrointestinal symptoms, abdominal
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Scientific Abstract

January 2025

Title: Understanding How a Simple Lung Test Can Guide Care for Children with Cystic Fibrosis
Authors
Lucy Perrem, Stephanie Jeanneret-Manning, Stephanie D Davis, Margaret Rosenfeld, Todd Edwards, Sanja Stanojevic, Felix Ratjen
References
J Cyst Fibros. 2025 Jan 11:S1569-1993(24)01852-6. doi: 10.1016/j.jcf.2024.12.001.
Keywords
Clinical utilty, LCI, Lung function, MBW, Maintenance therapy, Modulators, Withdrawal
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Scientific Abstract

January 2025

Title: Clinical characteristics of people with CF experiencing food insecurity
Authors
Heather Boas, Jesse Y Hsu, Allen Koshy, Semret Seyoum, Marsha Regenstein, Gina Hong, Olivia Dieni, Anne Willis, Clement L Ren
References
J Cyst Fibros. 2025 Jan 9:S1569-1993(24)01855-1. doi: 10.1016/j.jcf.2024.12.005
Keywords
Epidemiology, Health equity, Health-related social need, Nutrition, Pulmonary exacerbation, Social determinants of health
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Scientific Abstract

January 2025

Title: Understanding the Connection Between the Lungs and Kidneys in Cystic Fibrosis
Authors
Grace M Rosner, Himanshu B Goswami, Katherine Sessions, Lindsay K Mendyka, Brenna Kerin, Irma Vlasac, Diane Mellinger, Lorraine Gwilt, Thomas H Hampton, Martha Graber, Alix Ashare, William T Harris, Brock Christensen, Bruce A Stanton,, Agnieszka Swiatecka-Urban, Sladjana Skopelja-Gardner
References
J Cyst Fibros. 2025 Jan 2:S1569-1993(24)01858-7. doi: 10.1016/j.jcf.2024.12.007.
Keywords
Kidney injury, Lung-kidney, Neutrophils, Urine analysis
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Scientific Abstract