With the CF Research News, we aim to bridge the gap between people with CF and the researchers investigating CF and how best to treat those with the condition.
We want to provide access to patients, parents, relatives, friends and caregivers of patients with CF to all scientific work mainly published in the Journal of Cystic Fibrosis (JCF).

All PDF files published hereunder are lay version summaries of work published in the JCF.

March 2022

Title: High blood eosinophil counts are linked with worse symptoms in adults with cystic fibrosis
Authors
Si Cong Ye, Sameer Desai, Emma Karlsen, Eugenie Kwong, Pearce G. Wilcox, Bradley S. Quon
References
J Cyst Fibros. 2022 Mar 31;S1569-1993(22)00086-8. doi: 10.1016/j.jcf.2022.03.009.
Keywords
Biomarkers, Eosinophils, Outcomes, Patient-reported symptoms
Theme
Biomarkers, Care of patients with CF, Lung Disease and Infection
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Scientific Abstract

March 2022

Title: Club cell secretory protein is reduced in children with cystic fibrosis who have severe lung disease
Authors
Jing Zhai, Mary J Emond, Amber Spangenberg, Debra A Stern, Monica M Vasquez, Elizabeth E Blue, Kati J Buckingham, Duane L Sherrill, Marilyn Halonen, Ronald L Gibson, Margaret Rosenfeld, Scott D Sagel, Michael J Bamshad, Wayne J Morgan, Stefano Guerra
References
J Cyst Fibros. 2022 Mar 30;S1569-1993(22)00084-4. doi: 10.1016/j.jcf.2022.03.007.
Keywords
Club cell secretory protein, Lung function
Theme
Biomarkers, Care of patients with CF, Lung Disease and Infection
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Scientific Abstract

March 2022

Title: What makes lung function fall between childhood and adolescence
Authors
Nelufa Begum, Catherine A Byrnes, Joyce Cheney, Peter J Cooper, Emmanuelle Fantino, Nicholas Gailer, Keith Grimwood, Diana GutierrezCardenas, John Massie, Colin F Robertson, Peter D Sly, Harm Awm Tiddens, Claire E Wainwright, Robert S Ware
References
J Cyst Fibros. 2022 Mar 24;S1569-1993(22)00085-6. doi: 10.1016/j.jcf.2022.03.008.
Keywords
ACFBAL study, Aspergillus, CF-FAB study, Hospitalisation, Neutrophilic inflammation, Respiratory exacerbations
Theme
Care of patients with CF, Lung Disease and Infection, Pulmonology
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Scientific Abstract

March 2022

Title: Cystic fibrosis liver disease – A clinical challenge in the era of improved outcomes.
Authors
Ao Sasame, Diarmuid Stokes, Billy Bourke, Lucy Connolly, Emer Fitzpatrick, Marion Rowland
References
J Cyst Fibros. 2022 Mar;21(2):202-211. doi: 10.1016/j.jcf.2021.07.014. Epub 2021 Aug 8.
Keywords
Cystic fibrosis liver disease, mortality, Outcome, Systematic review
Theme
Care of patients with CF, Nutrition/Gastroenterology
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Scientific Abstract
Title: Serodiagnostic as a complement to bacterial culture in identification of Mycobacterium abscessus infections in cystic fibrosis patients
Authors
Vincent Le Moigne , Anne-Laure Roux, Hélène Mahoudo, Gaëtan Christien, Agnès Ferroni, Oana Dumitrescu, Gérard Lina, Jean-Philippe Bouchara, Patrick Plésiat, Jean-Louis Gaillard, Stéphane Canaan, Geneviève Héry-Arnaud, Jean-Louis Herrmann
References
J Cyst Fibros. 2022 Mar;21(2):353-360. doi: 10.1016/j.jcf.2021.08.019. Epub 2021 Sep 10.
Keywords
ELISA, Non-tuberculous mycobacteria, Serodiagnosis, Serology
Theme
Biomarkers, Lung Disease and Infection, Microbiology
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Scientific Abstract
Title: Multi-Organ MRI in Cystic Fibrosis
Authors
Kimberly McBennett, Christina J MacAskill, Elise Keshock, Maryam Ghadimi Mahani, Jaime Mata, Alexander J Towbin, Senthilkumar Sankararaman, Mitchell L Drumm, Xin Yu, Clement L Ren, Samya Z Nasr, Katherine Kutney, Chris A Flask
References
J Cyst Fibros. 2022 Mar;21(2):e148-e157. doi: 10.1016/j.jcf.2021.11.006.
Keywords
Heart, kidney, liver, lung, Magnetic Resonance Imaging, pancreas, Review
Theme
Care of patients with CF, Imaging
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Scientific Abstract

March 2022

Title: Elexacaftor-Tezacaftor- Ivacaftor improves sinonasal sinus in cystic fibrosis
Authors
Amanda L Stapleton, Adam J Kimple, Jennifer L Goralski, S Mehdi Nouraie, Barton F Branstetter, Amber D Shaffer, Joseph M Pilewski, Brent A Senior, Stella E Lee, Anna C Zemke
References
J Cyst Fibros. 2022 Mar 14;S1569-1993(22)00051-0. doi: 10.1016/j.jcf.2022.03.002.
Keywords
Highly effective modulator therapy, Sinus disease, Sinusitis
Theme
Care of patients with CF
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Scientific Abstract

March 2022

Title: Reduced levels of nitric oxide in cystic fibrosis airways may be caused by interleukin-1 beta
Authors
Gyde Nissen, Elad Ben-Meir, Matthias Kopp, Michelle Shaw, Felix Ratjen, Hartmut Grasemann
References
J Cyst Fibros. 2022 Mar 5;S1569-1993(22)00049-2. doi: 10.1016/j.jcf.2022.02.017.
Keywords
Airway inflammation, Ivacaftor, Nitric oxide
Theme
Care of patients with CF, Immunology
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Scientific Abstract

March 2022

Title: Intracranial mucous benign cyst causing bulging eye in a child with cystic fibrosis: a case report.
Authors
Cristina de Manuel Gómez, Ana Cecilia Morales Palacios, Olga de la Serna Blázquez, Pablo Vicente Morillo Carnero, María Elena Pérez Arenas, Sonia Milkova Ivanova, Marta Ruiz de Valbuena Maiz
References
J Cyst Fibros. 2022 Mar 1;S1569-1993(22)00048-0. doi: 10.1016/j.jcf.2022.02.016.
Keywords
Mucocele, Mucopyocele, Proptosis, Escherichia coli
Theme
Care of patients with CF
PDF icon CF Research News Article
Scientific Abstract