With the CF Research News, we aim to bridge the gap between people with CF and the researchers investigating CF and how best to treat those with the condition.
We want to provide access to patients, parents, relatives, friends and caregivers of patients with CF to all scientific work mainly published in the Journal of Cystic Fibrosis (JCF).

All PDF files published hereunder are lay version summaries of work published in the JCF.

March 2020

Title: Antibiofilm and mucolytic action of nitric oxide delivered as a gas or via macromolecular donor using in vitro and ex vivo models
Authors
Kaitlyn R. Rouillard, David B. Hill, Mark H. Schoenfisch
References
J Cyst Fibros. 2020 Mar 20;S1569-1993(20)30075-8. doi: 10.1016/j.jcf.2020.03.004
Keywords
Biofilm, Mucolytic, Mucus, Nitric oxide, Pseudomonas aeruginosa
PDF icon CF Research News Article
Scientific Abstract
Title: Go for It, Dream Big, Work Hard and Persist': A Message to the Next Generation of CF Leaders in Recognition of International Women's Day 2020
Authors
Mona Al Langawi, Cass Byrnes, Jane C Davies, Samia Hamouda, Madhulika Kabra, Samia Z Rached, Dorota Sands, Michal Shteinberg, Jennifer Taylor-Cousar, Elizabeth Tullis, Claire Wainwright
References
J Cyst Fibros. 2020 Mar 7;S1569-1993(20)30070-9. doi: 10.1016/j.jcf.2020.02.021.
Keywords
Career, Childcare, Gender, Leadership, Promotion, women
PDF icon CF Research News Article
Scientific Abstract

March 2020

Title: Total bacterial load, inflammation, and structural lung disease in paediatric cystic fibrosis
Authors
Steven L. Taylor, Lex E.X. Leong, Kerry L. Ivey, Steve Wesselingh, Keith Grimwood, Claire E. Wainwright, Geraint B. Rogers, On behalf of the Australasian Cystic Fibrosis Bronchoalveolar Lavage (ACFBAL) study group
References

J Cyst Fibros. 2020 Mar 18; - DOI: 10.1016/j.jcf.2020.03.008

Keywords
Bronchoalveolar lavage, Computed tomography, Infection, microbiota, Paediatric, quantitative polymerase chain reaction
PDF icon CF Research News Article
Scientific Abstract

March 2020

Title: Intrinsic Alterations in Peripheral Neutrophils From Cystic Fibrosis Newborn Piglets
Authors
Déborah Bréa, Laura Soler, Isabelle Fleurot, Sandrine Melo, Claire Chevaleyre, Mustapha Berri, Valérie Labas, Ana-Paula Teixeira-Gomes, Julien Pujo, Nicolas Cenac, Andrea Bähr, Nikolai Klymiuk, Antoine Guillon, Mustapha Si-Tahar, Ignacio Caballero
References
J Cyst Fibros. 2020 Mar 9;S1569-1993(20)30065-5. doi: 10.1016/j.jcf.2020.02.016.
Keywords
CFTR, ICM-MS, Neutrophils, Pig model
PDF icon CF Research News Article
Scientific Abstract

March 2020

Title: Outcomes of pregnancy in women with cystic fibrosis (CF) taking CFTR modulators - an international survey
Authors
Edward F Nash, Peter G Middleton, Jennifer L Taylor-Cousar
References
J Cyst Fibros 2020 Mar 6 -  doi: 10.1016/j.jcf.2020.02.018.
Keywords
Breastfeeding, CFTR, infant, Modulators, pregnancy
PDF icon CF Research News Article
Scientific Abstract

March 2020

Title: Ebselen attenuates tobramycin-induced ototoxicity in mice
Authors
Rende Gu, Ryan J Longenecker, Jennifer Homan, Jonathan Kil
References
J Cyst Fibros. 2020 Mar 5;S1569-1993(20)30063-1. doi: 10.1016/j.jcf.2020.02.014.
Keywords
Aminoglycoside, Auditory brainstem response, Ebselen, Hearing loss, Ototoxicity, Tobramycin
PDF icon CF Research News Article
Scientific Abstract