All Resources

This page provides filters and search facilities across all types of CF resources contained within the ECFS website.

Additionally, you can visit the specific resource type pages as follows:

More information on CF publications can be found here: Publications

September 2020

Title: Safety and Efficacy of Lenabasum in a Phase 2 Randomized, Placebo-Controlled Trial in Adults with Cystic Fibrosis
Authors
James F Chmiel, Patrick Flume, Damian G Downey, Allen J Dozor, Carla Colombo, Henryk Mazurek, Ewa Sapiejka, Marta Rachel, Scott Constantine, Brian Conley, Nancy Dgetluck, Quinn Dinh, Barbara White, J Stuart Elborn, Lenabasum JBT101-CF-001 Study Group
References
J Cyst Fibros. 2020 Sep 30;S1569-1993(20)30873-0. doi: 10.1016/j.jcf.2020.09.008.
Keywords
Lenabasum, Pulmonary exacerbations, Safety
PDF icon CF Research News Article
Scientific Abstract

September 2020

Title: Evidence of early increased sialylation of airway mucins and defective mucociliary clearance in CFTR-/- deficient piglets
Authors
Ignacio Caballero, Bélinda Ringot-Destrez, Mustapha Si-Tahar, Pascal Barbry, Antoine Guillon, Isabelle Lantier, Mustapha Berri, Claire Chevaleyre, Isabelle Fleurot, Céline Barc, Reuben Ramphal, Nicolas Pons, Agnès Paquet, Kévin Lebrigand, Carole Baron, Andrea Bähr, Nikolai Klymiuk, Renaud Léonard, Catherine Robbe-Masselot
References
J Cyst Fibros. 2020 Sep 23;S1569-1993(20)30868-7. doi: 10.1016/j.jcf.2020.09.009.
Keywords
CFTR, Mucin glycosylation, Mucociliary transport, Sus scrofa
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Scientific Abstract

September 2020

Title: A phase 3, double-blind, parallel-group study to evaluate the efficacy and safety of tezacaftor in combination with ivacaftor in participants 6 through 11 years of age with cystic fibrosis homozygous for F508del or heterozygous for the F508del-CFTR mutati
Authors
Jane C Davies, Isabelle Sermet-Gaudelus, Lutz Naehrlich, R Scott Harris, Daniel Campbell, Neil Ahluwalia, Christopher Short, Eric Haseltine, Paul Panorchan, Clare Saunders, Caroline A Owen, Claire E Wainwright, VX16-661-115 Investigator Group
References
J Cyst Fibros . 2020 Sep 21;S1569-1993(20)30811-0. doi: 10.1016/j.jcf.2020.07.023.
Keywords
Clinical trial, F508del-CFTR mutation, Ivacaftor, Lung clearance index, Residual function CFTR mutation, Tezacaftor
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Scientific Abstract

September 2020

Title: Tobacco Smoke Exposure and Socioeconomic Factors Are Independent Predictors of Pulmonary Decline in Pediatric Cystic Fibrosis
Authors
Gabriela R Oates, Elizabeth Baker, Steven M Rowe, Hector H Gutierrez, Michael S Schechter, Wayne Morgan, William T Harris
References
J Cyst Fibros. 2020 Sep;19(5):783-790. doi: 10.1016/j.jcf.2020.02.004. Epub 2020 Feb 17.
Theme
Care of patients with CF, Psychosocial, Pulmonology
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Scientific Abstract
Title: Anti-inflammatory effects of lenabasum, a cannabinoid receptor type 2 agonist, on macrophages from cystic fibrosis
Authors
Abdullah A. Tarique , Tama Evron, George Zhang, Mark A. Tepper, Mohammed M. Morshed, Isabella S.G. Andersen, Nelufa Begum, Peter D. Sly, Emmanuelle Fantino
References
J Cyst Fibros. 2020 Sep;19(5):823-829. doi: 10.1016/j.jcf.2020.03.015. Epub 2020 May 6. 
Keywords
Anti-inflammatory, CB2 agonists, Cannabinoid 2 receptor (CB2), Endocytosis, Macrophage polarization, Macrophage responses, Phagocytosis
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Scientific Abstract

September 2020

Title: What is the value of lung function testing in infants with cystic fibrosis?
Authors
M Pollak, M Shaw, S Balkovec, D Wilson, K Kowalik, P Subbarao, F Ratjen
References
 J Cyst Fibros. 2020 Sep 17;S1569-1993(20)30867-5. doi: 10.1016/j.jcf.2020.09.005. Online ahead of print.
PDF icon CF Research News Article
Scientific Abstract

September 2020

Title: Trends in nontuberculous mycobacteria infection in children and young people with cystic fibrosis
Authors
Noreen Zainal Abidin, Aaron Ions Gardner, Hannah-Louise Robinson, Iram J Haq, Matthew F Thomas, Malcolm Brodlie
References
J Cyst Fibros. 2020 Sep 16;S1569-1993(20)30872-9. doi: 10.1016/j.jcf.2020.09.007.
Keywords
nontuberculous mycobacteria, Pediatrics
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Scientific Abstract

September 2020

Title: Sputum for viral diagnosis in cystic fibrosis patients
Authors
Emilie Cardot-Martin, Hélène Le Guillou-Guillemette, Rozenn Le Berre, Sophie Ramel, Jean Le Bihan, Dominique Grenet, Eric Farfour, Françoise Troussier, Thierry Urban, Lisa Billard, Léa Pilorgé, Adissa Minoui-Tran, Christopher Payan, Marie-Reine Munck, Genevieve Héry-Arnaudak, and Sophie Valletai* on behalf of the MucoMicrobes study group
References
J Cyst Fibros. 2020 Sep 14;S1569-1993(20)30865-1. doi: 10.1016/j.jcf.2020.09.003.
Keywords
Influenza virus, Multiplex molecular diagnosis, Respiratory virus, Sputum, nasopharyngeal
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Scientific Abstract

September 2020

Title: Delayed glucose peak and elevated 1-hour glucose on the oral glucose tolerance test identify youth with cystic fibrosis with lower oral disposition index
Authors
Kalie L Tommerdahl, John T Brinton, Tim Vigers, Melanie Cree-Green, Philip S Zeitler, Kristen J Nadeau, Christine L Chan
References
J Cyst Fibros. 2020 Sep 11;2111. doi: 10.1016/j.jcf.2020.08.020. Online ahead of print.
Keywords
Cystic fibrosis-related diabetes, Oral disposition index, Oral glucose tolerance test, Pediatrics, screening
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Scientific Abstract
Title: Delayed glucose peak and elevated 1-hour glucose on the oral glucose tolerance test identify youth with cystic fibrosis with lower oral disposition index
Authors
Kalie L Tommerdahl, John T Brinton, Tim Vigers, Melanie Cree-Green, Philip S Zeitler, Kristen J Nadeau, Christine L Chan
References
J Cyst Fibros. 2020 Sep 11;2111. doi: 10.1016/j.jcf.2020.08.020. Online ahead of print.
Keywords
Cystic fibrosis-related diabetes, Oral disposition index, Oral glucose tolerance test, Pediatrics, screening
PDF icon CF Research News Article
Scientific Abstract

September 2020

Title: Baseline CF disease severity has an adverse impact on pregnancy and infant outcomes, but does not impact disease progression
Authors
Malena Cohen-Cymberknoh, Bar Gindi Reiss, Joel Reiter, Noah Lechtzin, Joel Melo, Gema Pérez, Hannah Blau, Huda Mussaffi, Hagit Levine, Lea Bentur, Michal Gur, Galit Livnat, Javier Perez Miranda, Eva Polverino, Francesco Blasi, Stefano Aliberti, Micha Aviram, Inbal Golan Tripto, Elie Picard, Michal Novoselsky, Hagai Amsalem, Drorit Ochner, Eitan Kerem, Michal Shteinberg
References
J Cyst Fibros. 2020 Sep 9;S1569-1993(20)30864-X. doi: 10.1016/j.jcf.2020.09.002.
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Scientific Abstract

September 2020

Title: Lumacaftor/ivacaftor therapy fails to increase insulin secretion in F508del/F508del CF patients
Authors
Amir Moheet, Daniel Beisang, Lin Zhang, Scott D Sagel, Jill M VanDalfsen, Sonya L Heltshe, Carla Frederick, Michelle Mann, Nicholas Antos, Joanne Billings, Steven M Rowe, Antoinette Moran, PROSPECT Investigators of the Cystic Fibrosis Foundation, Therapeutics Development Network
References
J Cyst Fibros. 2020 Sep 8;S1569-1993(20)30862-6. doi: 10.1016/j.jcf.2020.09.001. 
Keywords
CFRD, insulin secretion, Orkambi
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Scientific Abstract

September 2020

Title: Factors influencing clinical trial participation for adult and pediatric patients with cystic fibrosis
Authors
Marissa Lee, Xun Yang Hu, Sameer Desai, Eugenie Kwong, Joey Fu, Eri Flores, Lynda Lazosky, Pearce G Wilcox, Maggie Mcllwaine, Mark Chilvers, Connie Yang, Jonathan H Rayment, Bradley S Quon
References
J Cyst Fibros. 2020 Sep 5;S1569-1993(20)30857-2. doi: 10.1016/j.jcf.2020.08.019. Online ahead of print.
Keywords
Barriers, clinical trials, Facilitators, research
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Scientific Abstract

September 2020

Title: Aerosolized lancovutide in adolescents (≥12 years) and adults with cystic fibrosis - a randomized trial
Authors
Ernst Eber, Maria Trawinska-Bartnicka, Dorota Sands, Gabriel Bellon, Uwe Mellies, Katalin Bolbás, Serena Quattrucci, Henryk Mazurek, Rudolf Widmann, Christian Schoergenhofer, Bernd Jilma, Felix Ratjen
References
J Cyst Fibros. 2020 Sep 1;S1569-1993(20)30830-4. doi: 10.1016/j.jcf.2020.08.014.
Keywords
Clinical trial, Lancovutide, Lung function, Quality of life
PDF icon CF Research News Article
Scientific Abstract