Title: Randomized Trial of Efficacy and Safety of Dornase Alfa Delivered by eRapid Nebulizer in Cystic Fibrosis Patients.
Authors Gregory S. Sawicki, Will Chou, Karina Raimundo, Ben Trzaskoma, Michael W. Konstan
References J Cyst Fibros. 2015 Apr 25. pii: S1569-1993(15)00103-4. doi: 10.1016/j.jcf.2015.04.003
Keywords Nebulizers, Dornase alfa
Title: Deleterious impact of hyperglycemia on cystic fibrosis airway ion transport and epithelial repair.
Authors Claudia Bilodeau, Olivier Bardou, Émilie Maillé, Yves Berthiaume, Emmanuelle Brochiero
References J Cyst Fibros. 2015 Apr 24. pii: S1569-1993(15)00102-2
Keywords Airways, Epithelial repair, K+ channels, CFTR, Cystic fibrosis, Diabetes
Title: Assessment of Epithelial Sodium Channel Variants in Nonwhite Cystic Fibrosis Patients with Non-Diagnostic CFTR Genotypes
Authors Marie-Luise Brennan, Lynn M. Pique, Iris Schrijver
References J Cyst Fibros. 2015 Apr 17. pii: S1569-1993(15)00101-0. doi: 10.1016/j.jcf.2015.04.001
Keywords Epithelial sodium channel, ENaC, SCNN1, Molecular diagnosis, CFTR, Nonwhite
Theme Diagnosis/Screening
Title: Cystic fibrosis transmembrane conductance regulator gene variants are associated with autoimmune pancreatitis and slow response to steroid treatment.
Authors Ming-Chu Chang, I-Shiow Jan, Po-Chin Liang, Yung-Ming Jeng, Ching-Yao Yang, Yu-Wen Tien, Jau-Min Wong, Yu-Ting Chang
References J Cyst Fibros. 2015 Apr 10. pii: S1569-1993(15)00064-8.
Keywords Autoimmune pancreatitis (AIP), Cystic fibrosis transmembrane conductance regulator (CFTR), Next-generation sequencing (NGS) response to steroid treatment
Theme Nutrition/Gastroenterology
Title: Use of ibuprofen to assess inflammatory biomarkers in induced sputum: Implications for clinical trials in cystic fibrosis.
Authors Chmiel JF, Konstan MW, Accurso FJ, Lymp J, Mayer-Hamblett N, VanDevanter DR, Rose LM, Ramsey BW
References J Cyst Fibros. 2015 Apr 10. pii: S1569-1993(15)00062-4. doi: 10.1016/j.jcf.2015.03.007
Keywords Biomarkers, Induced sputum, Inflammation, Ibuprofen, Anti-inflammatory drugs
Title: Strain Rate Echocardiography Uncovers Subclinical Left Ventricular Dysfunction in Cystic Fibrosis.
Authors Zachary M Sellers, Lori McGlocklin, Andrea Brasch
References J Cyst Fibros. 2015 Apr 9. pii: S1569-1993(15)00065-X
Keywords Left ventricle, Heart function, Echocardiography, Strain imaging
