Updated 17 February 2025

Introduction

Please find herewith an overview of clinical trials that are ongoing in hospitals that are part of the ECFS Clinical Trials Network (CTN).

Here you will find the full list of our Clinical Trials Network CF centres.

Studies only run in our CTN sites after a formal review of the study protocol and approval by a committee of experts (comprised of both adult and paediatric specialist CF clinicians, patient organisation representatives and patient/family reviewers). This does not mean that all CTN centres will participate in a specific study. Some CTN approved studies also run in additional centres that are not part of the CTN network. A complete list of participating sites can be found on the specific www.clinicaltrials.gov (link is external) that is mentioned on each study overview sheet.

If you wish to participate in some of the trials listed here, please discuss this with your treating physician/doctor/healthcare team.

The overview lists the studies under the headings: "recruitment started" or under "recruitment finished". In addition, the studies are categorized according to the drug's mechanism of action, using the following headings:

Genetic Therapy
Restore CFTR Protein
Mucociliary Clearance
Anti-Inflammatory
Anti-Infective
Nutritional-GI
Behavioural Interventions
Observational
Other

If you would like more detailed information on a particular study, please go to www.clinicaltrials.gov for detailed and up to date information on study background, eligibility criteria, study design, outcome measures, study status, participating sites, sponsor contact information and timelines.

You can also contact the CTN coordinating centre for any additional information:
ECFS-CTN@uzleuven.be (link sends e-mail)