The ECFS-CTN cannot guarantee that the information provided here is comprehensive. Please go to the ClinicalTrials.gov link for detailed and up-to-date information on study background, eligibility criteria, study design, outcome measures, study status, participating sites, sponsor contact information and timelines.

You can also contact the CTN coordinating centre for additional information: ECFS-CTN@uzleuven.be

Study Name on
ClinicalTrials.gov (link is external)
A Study Evaluating the Long-term Safety of VX-445 Combination Therapy.
This study is only for patients currently participating in study VX17-659-105
Study Drug elexacaftor (ELX, VX-445) in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA)
Type of Study Drug CFTR modulator
Study Title A Phase 3, Open-label Study Evaluating the Long-term Safety of VX-445 Combination Therapy in Subjects With Cystic Fibrosis
Study Phase3
Study Sponsor Vertex

Link on
clinicaltrials.gov (link is external)

https://clinicaltrials.gov/ct2/show/NCT04043806

Participating ECFS-CTN sites Please contact ecfs-ctn@uzleuven.be for most recent sitelist
Age 12 Years and older