The ECFS-CTN cannot guarantee that the information provided here is comprehensive. Please go to the ClinicalTrials.gov link for detailed and up-to-date information on study background, eligibility criteria, study design, outcome measures, study status, participating sites, sponsor contact information and timelines.

You can also contact the CTN coordinating centre for additional information: ECFS-CTN@uzleuven.be

Study TitleA Phase IIb, Multicentre, Randomised, Double-Blind, Placebo-Controlled, Crossover Study to Evaluate the Efficacy and Safety of Dirocaftor/Posenacaftor/Nesolicaftor in Subjects with Cystic Fibrosis Aged 18 Years or Older (CHOICES)
Study Drugdirocaftor/posenacaftor/nesolicaftor
Type of Study DrugCFTR Modulation
Study Phase2b
Study SponsorUniversity Medical Center Utrecht
Link in registry(ies)

https://euclinicaltrials.eu/search-for-clinical-trials/?lang=en&EUCT=2022-500410-26-01

https://clinicaltrials.gov/study/NCT06468527

Participating ECFS-CTN sitesPlease contact ecfs-ctn@uzleuven.be for most recent sitelist
AgeAdult patients