LungAnalysis CT core laboratory

LungAnalysis CT core laboratory 

LungAnalysis – Image Analysis Core Laboratory serves as the ECFS-CTN Computed Tomography (CT) Core Laboratory for standardization of chest CT image acquisition and centralized image analysis for clinical research and trials. Since 2012, LungAnalysis provides training services for spirometer-guided and technician-controlled chest CT scan procedures, ensuring standardized chest CT image acquisition. LungAnalysis also offers chest CT image analysis services for both investigator- and sponsor-initiated studies in clinical research and trials.

Between 2012 and 2015, LungAnalysis led the standardization of chest CT image acquisition across 16 ECFS-CTN sites as part of the SCIFI-CF study (Standardized Chest Imaging Framework for Interventions and Personalized Medicine in CF – Kuo et al., Eur Respir J 2016). This initiative enabled the ECFS-CTN to conduct multiple clinical research and trials incorporating chest CT related outcome measures.

In 2020, LungAnalysis was designated as the CT Expert Center for the ECFS-CTN to lead the SCIFI-II study, which successfully standardized and (re)certified all 57 ECFS-CTN sites for spirometer-guided and technician-controlled chest CT image acquisition (this pre-dates the recent expansion of the Network to 68 sites). This initiative resulted in the development of site- and scanner-specific CT scanning protocols for all participating sites. The project was a collaborative effort, with contributions from experts at the Department of Radiology and Nuclear Medicine at Erasmus MC.