The ECFS-CTN cannot guarantee that the information provided here is comprehensive. Please go to the ClinicalTrials.gov link for detailed and up-to-date information on study background, eligibility criteria, study design, outcome measures, study status, participating sites, sponsor contact information and timelines.

You can also contact the CTN coordinating centre for additional information: ECFS-CTN@uzleuven.be (link sends e-mail)

Study Name on
ClinicalTrials.gov (link is external)
Roll-Over Study of Ivacaftor in Cystic Fibrosis Pediatric Subjects With a CF Transmembrane Conductance Regulator Gene (CFTR) Gating Mutation
Study DrugIvacaftor (VX-770)
Type of Study DrugCFTR Modulation
Study TitleA Phase 3, 2-Arm, Roll-Over Study to Evaluate the Long-term Safety and Pharmacodynamics of Ivacaftor Treatment in Pediatric Subjects With Cystic Fibrosis and a CFTR Gating Mutation
Study Phase3
Study SponsorVertex

Link on
clinicaltrials.gov (link is external)

http://clinicaltrials.gov/ct2/show/NCT01946412 (link is external)

Participating ECFS-CTN sitesUK: London
Age2 Years and older