The ECFS-CTN cannot guarantee that the information provided here is comprehensive. Please go to the link for detailed and up-to-date information on study background, eligibility criteria, study design, outcome measures, study status, participating sites, sponsor contact information and timelines.

You can also contact the CTN coordinating centre for additional information:

Study Name on (link is external)
A Study Evaluating the Safety and Efficacy of VX-440 Combination Therapy in Subjects With Cystic Fibrosis
Study Drug Tezacaftor, Ivacaftor, VX-440
Type of Study Drug CFTR Modulator
Study Title Saline Hypertonic in Preschoolers With Cystic Fibrosis and Lung Structure as Measured by Computed Tomography (CT)
Study Phase 2
Study Sponsor Vertex

Link on (link is external)

Participating ECFS-CTN sites Please contact for most recent sitelist
Age 12 Years and older