CFTR/Basic Science | Page 3 | European Cystic Fibrosis Society (ECFS)

Restoration of the chloride and bicarbonate (soda) transport function in cystic fibrosis by Kaftrio

An in-depth study of the CFTR gene enables selection of CFTR therapies for almost all individuals with CF

Damage in the cell lining of the airways in cystic fibrosis

Exploring new treatment options for people with cystic fibrosis with severe stop mutations

Drug development for Cystic Fibrosis patients carrying the 3849+10kb C-to-T splicing mutation

Pilot trial of tobramycin inhalation powder in cystic fibrosis patients with chronic Burkholderia cepacia complex infection

Bone demineralization is improved by ivacaftor in patients with cystic fibrosis carrying the p.Gly551Asp mutation

Potentiator synergy in rectal organoids carrying S1251N, G551D or F508del CFTR mutations

Evaluation of a systems biology approach to identify pharmacological correctors of the mutant CFTR chloride channel

Creation and characterization of an airway epithelial cell line for stable expression of CFTR variants