Publications

SOPs, available on the ECFS Education Website under CTN Resources (or by request from ecfs-ctn@uzleuven.be or kate.hill@qub.ac.uk )

  • ECFS CTN 4.1/001/V2 Isolation, cultivation and application of primary epithelial cells obtained by nasal brushing SOP.
  • ECFS CTN 4.1/002 Transepithelial electrical measurements with the Ussing Chamber SOP.
  • ECFS CTN 4.1/003 SOP for Certification for Transepithelial electrical measurements with the Ussing Chamber.

Tomati V, Capurro V, Pesce E, Pastorino C, Sondo E, Lena M, Borrelli A, Cresta F, Pantano S, Collini F, Ripani P, Terlizzi V, Fevola C, Costa S, Lucanto MC, Zara F, Bandiera T, Bocciardi R, Castellani C, Galietta LJV, Pedemonte N. Pharmacological rescue of the G85E CFTR variant by preclinical and approved modulators. Front Pharmacol. 2024 Nov 18;15:1494327. doi: 10.3389/fphar.2024.1494327. PMID: 39624835; PMCID: PMC11608983.

Corrao F, Kelly-Aubert M, Sermet-Gaudelus I, Semeraro M. Unmet challenges in cystic fibrosis treatment with modulators. Expert Rev Respir Med. 2024 Mar-Apr;18(3-4):145-157. doi: 10.1080/17476348.2024.2357210. Epub 2024 May 21. PMID: 38755109.

Zajac M, Lepissier A, Dréano E, Chevalier B, Hatton A, Kelly-Aubert M, Guidone D, Planelles G, Edelman A, Girodon E, Hinzpeter A, Crambert G, Pranke I, Galietta LJV, Sermet-Gaudelus I. Putting bicarbonate on the spot: pharmacological insights for CFTR correction in the airway epithelium. Front Pharmacol. 2023 Dec 11;14:1293578. doi: 10.3389/fphar.2023.1293578. PMID: 38149052; PMCID: PMC10750368.

Pion A, Kavanagh E, Joynt AT, Raraigh KS, Vanscoy L, Langfelder-Schwind E, McNamara J, Moore B, Patel S, Merlo K, Temme R, Capurro V, Pesce E, Merlo C, Pedemonte N, Cutting GR, Sharma N. Investigation of CFTR Function in Human Nasal Epithelial Cells Informs Personalized Medicine. Am J Respir Cell Mol Biol. 2024 Nov;71(5):577-588. doi: 10.1165/rcmb.2023-0398OC. PMID: 39012815; PMCID: PMC11568479.

Guidone D, de Santis M, Pesce E, Capurro V, Pedemonte N, Galietta LJV. The apical mucus layer alters the pharmacological properties of the airway epitheliumy. J Physiol. 2025 Mar 6. doi: 10.1113/JP287891. Epub ahead of print. PMID: 40047394.

Dreano E, Burgel PR, Hatton A, Bouazza N, Chevalier B, Macey J, Leroy S, Durieu I, Weiss L, Grenet D, Stremler N, Ohlmann C, Reix P, Porzio M, Roux Claude P, Rémus N, Douvry B, Montcouquiol S, Cosson L, Mankikian J, Languepin J, Houdouin V, Le Clainche L, Guillaumot A, Pouradier D, Tissot A, Priou P, Mély L, Chedevergne F, Lebourgeois M, Lebihan J, Martin C, Zavala F, Da Silva J, Lemonnier L, Kelly-Aubert M, Golec A, Foucaud P, Marguet C, Edelman A, Hinzpeter A, de Carli P, Girodon E, Sermet-Gaudelus I, Pranke I; French CF Reference Network study group. Theratyping cystic fibrosis patients to guide elexacaftor/tezacaftor/ivacaftor out-of-label prescription. Eur Respir J. 2023 Oct 19;62(4):2300110. doi: 10.1183/13993003.00110-2023. PMID: 37696564.

Terlizzi V, Pesce E, Capurro V, Tomati V, Lena M, Pastorino C, Bocciardi R, Zara F, Centrone C, Taccetti G, Castellani C and Pedemonte N. Clinical Consequences and Functional Impact of the Rare S737F CFTR Variant and Its Responsiveness to CFTR Modulators. International Journal of Molecular Sciences. 2023; 24(7):6576. https://doi.org/10.3390/ijms24076576