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CFTR modulators

Pregnancy outcomes in women with cystic fibrosis and poor pulmonary function

  • Read more about Pregnancy outcomes in women with cystic fibrosis and poor pulmonary function

Building global development strategies for cf therapeutics during a transitional cftr modulator era

  • Read more about Building global development strategies for cf therapeutics during a transitional cftr modulator era

CFTR modulator therapy for cystic fibrosis caused by the rare c.3700A>G mutation

  • Read more about CFTR modulator therapy for cystic fibrosis caused by the rare c.3700A>G mutation

Amplifiers co-translationally enhance CFTR biosynthesis via PCBP1-mediated regulation of CFTR mRNA

  • Read more about Amplifiers co-translationally enhance CFTR biosynthesis via PCBP1-mediated regulation of CFTR mRNA

Females with Cystic Fibrosis have a larger decrease in sweat chloride in response to lumacaftor/ivacaftor compared to males

  • Read more about Females with Cystic Fibrosis have a larger decrease in sweat chloride in response to lumacaftor/ivacaftor compared to males

Speeding up access to new drugs for Cystic Fibrosis: Considerations for clinical trial design and delivery

  • Read more about Speeding up access to new drugs for Cystic Fibrosis: Considerations for clinical trial design and delivery

R560S: a class II CFTR mutation that is not rescued by current modulators

  • Read more about R560S: a class II CFTR mutation that is not rescued by current modulators

Measured fetal and neonatal exposure to Lumacaftor and Ivacaftor during pregnancy and while breastfeeding

  • Read more about Measured fetal and neonatal exposure to Lumacaftor and Ivacaftor during pregnancy and while breastfeeding

Drugs during pregnancy and breast feeding in women diagnosed with Cystic Fibrosis – an update

  • Read more about Drugs during pregnancy and breast feeding in women diagnosed with Cystic Fibrosis – an update

Retrospective observational study of French patients with cystic fibrosis and a Gly551Asp-CFTR mutation after 1 and 2 years of treatment with ivacaftor in a real-world setting

  • Read more about Retrospective observational study of French patients with cystic fibrosis and a Gly551Asp-CFTR mutation after 1 and 2 years of treatment with ivacaftor in a real-world setting
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