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CFTR modulator

Lumacaftor/ivacaftor reduces exacerbations in adults homozygous for Phe508del mutation with severe lung disease

  • Read more about Lumacaftor/ivacaftor reduces exacerbations in adults homozygous for Phe508del mutation with severe lung disease

Accumulation and persistence of Ivacaftor in airway epithelia with prolonged treatment

  • Read more about Accumulation and persistence of Ivacaftor in airway epithelia with prolonged treatment

CFTR activity is enhanced by the novel corrector GLPG2222, given with and without ivacaftor in two randomized trials

  • Read more about CFTR activity is enhanced by the novel corrector GLPG2222, given with and without ivacaftor in two randomized trials

GLPG1837, a CFTR potentiator, in p.Gly551Asp (G551D)-CF patients: An open-label, single-arm, phase 2a study (SAPHIRA1)

  • Read more about GLPG1837, a CFTR potentiator, in p.Gly551Asp (G551D)-CF patients: An open-label, single-arm, phase 2a study (SAPHIRA1)

Disease Progression in Patients with Cystic Fibrosis Treated with Ivacaftor: Data From National US and UK Registries

  • Read more about Disease Progression in Patients with Cystic Fibrosis Treated with Ivacaftor: Data From National US and UK Registries

Concentration of Fractional Excretion of Nitric Oxide (FENO): A Potential Airway Biomarker of Restored CFTR Function

  • Read more about Concentration of Fractional Excretion of Nitric Oxide (FENO): A Potential Airway Biomarker of Restored CFTR Function

Long-term improvement of lung clearance index in patients with mild cystic fibrosis lung disease: Does hypertonic saline play a role?

  • Read more about Long-term improvement of lung clearance index in patients with mild cystic fibrosis lung disease: Does hypertonic saline play a role?
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