With the CF Research News, we aim to bridge the gap between people with CF and the researchers investigating CF and how best to treat those with the condition.
We want to provide access to patients, parents, relatives, friends and caregivers of patients with CF to all scientific work mainly published in the Journal of Cystic Fibrosis (JCF).

All PDF files published hereunder are lay version summaries of work published in the JCF.

June 2019

Title: Dissociation of Systemic and Mucosal Autoimmunity in Cystic Fibrosis
Authors
Theprungsirikul, J, Skopelja-Gardner, S, Meagher, R. E, Clancy, J. P, Zemanick, E.T, Ashare, A, Rigby, W. F. C
References
J Cyst Fibros. 2019 Jun 28. pii: S1569-1993(19)30807-0. doi: 10.1016/j.jcf.2019.06.006. 
PDF icon JCF-D-19-00097R1_FINAL_Rigby_100719.pdf
Scientific Abstract
Title: Dissociation of Systemic and Mucosal Autoimmunity in Cystic Fibrosis
Authors
Theprungsirikul, J, Skopelja-Gardner, S, Meagher, R. E, Clancy, J. P, Zemanick, E.T, Ashare, A, Rigby, W. F. C
References
J Cyst Fibros. 2019 Jun 28. pii: S1569-1993(19)30807-0. doi: 10.1016/j.jcf.2019.06.006. 
Keywords
autoimmunity, Bactericidal/permeability-increasing protein (BPI), Pseudomonas aeruginosa
PDF icon CF Research News Article
Scientific Abstract

June 2019

Title: Predictors of Pulmonary Exacerbation Treatment in Cystic Fibrosis
Authors
Don B Sanders, Joshua S Ostrenga, Margaret Rosenfeld, Aliza K Fink, Michael S Schechter, Gregory S Sawicki, Patrick A Flume, Wayne J Morgan
References
J Cyst Fibros 2019 Jun 27 - DOI: 10.1016/j.jcf.2019.06.008
PDF icon CF Research News Article
Scientific Abstract

June 2019

Title: Variation in lung function and nutritional decline in cystic fibrosis by genotype: An analysis of the Canadian Cystic Fibrosis Registry
Authors
Garvin J. Leung, Ting J. Cho, Thomas Kovesi, Jemila S. Hamid, Dhenuka Radhakrishnan
References
J Cyst Fibros. 2019 Jun 25. pii: S1569-1993(19)30812-4. doi: 10.1016/j.jcf.2019.06.007
PDF icon JCF-D-19-00141R1_FINAL_Radhakrishnan_150719.pdf
Scientific Abstract
Title: Variation in lung function and nutritional decline in cystic fibrosis by genotype: An analysis of the Canadian Cystic Fibrosis Registry
Authors
Garvin J. Leung, Ting J. Cho, Thomas Kovesi, Jemila S. Hamid, Dhenuka Radhakrishnan
References
J Cyst Fibros. 2019 Jun 25. pii: S1569-1993(19)30812-4. doi: 10.1016/j.jcf.2019.06.007
Keywords
Body mass index, Epidemiology, Lung function
PDF icon CF Research News Article
Scientific Abstract

June 2019

Title: Do current clinical trials in cystic fibrosis match the priorities of patients and clinicans? A systematic review.
Authors
Kalaitzis IS, Rowbotham NJ, Smith SJ, Smyth AR
References
J Cyst Fibros. 2019 Jun 21. pii: S1569-1993(19)30806-9. doi: 10.1016/j.jcf.2019.06.005.
Keywords
Clinical trial, Research priority
PDF icon CF Research News Article
Scientific Abstract

June 2019

Title: Disease Progression in Patients with Cystic Fibrosis Treated with Ivacaftor: Data From National US and UK Registries
Authors
Volkova N, Moy K, Evans J, Campbell D, Tian S, Simard C, Higgins M, Konstan MW, Sawicki GS, Elbert A, Charman SC, Marshall BC, Bilton D
References
J Cyst Fibros. 2019 Jun 10. pii: S1569-1993(19)30767-2. doi: 10.1016/j.jcf.2019.05.015. 
Keywords
CF complications, CF disease progression, CFTR, CFTR modulator, Ivacaftor
PDF icon CF Research News Article
Scientific Abstract

June 2019

Title: Antisense oligonucleotide eluforsen is safe and improves respiratory symptoms in F508DEL cystic fibrosis.
Authors
Drevinek P, Pressler T, Cipolli M, De Boeck K, Schwarz C, Bouisset F, Boff M, Henig N, Paquette-Lamontagne N, Montgomery S, Perquin J, Tomkinson N, den Hollander W, Elborn JS
References
J Cyst Fibros. 2019 Jun 7. pii: S1569-1993(19)30766-0. doi: 10.1016/j.jcf.2019.05.014
Keywords
Antisense oligonucleotide, CFQ-R RSS, Clinical trial, Delta F508, Pulmonary Medicine
PDF icon CF Research News Article
Scientific Abstract

June 2019

Title: Non-fasting bioelectrical impedance analysis in cystic fibrosis: Implications for clinical practice and research
Authors
Hollander-Kraaijeveld FM, Lindeman Y, de Roos NM, Burghard M, van de Graaf EA, Heijerman HGM
References
J Cyst Fibros. 2019 Jun 5. pii: S1569-1993(19)30772-6. doi: 10.1016/j.jcf.2019.05.018
Keywords
Anthropometry, Body composition, FEV1%pred, Non-fasting, Single frequency bioelectrical impedance analysis
PDF icon CF Research News Article
Scientific Abstract
Title: Blood Biomarkers to Predict Short-term Pulmonary Exacerbation Risk in Children and Adolescents with CF: A Pilot Study
Authors
Amrit Singh, Mary He, Virginia Chen, Zsuzsanna Hollander, Scott J. Tebbutt, Raymond T. Ng, Bruce M. McManus, Don D. Sin, Felix Ratjen, Bradley S. Quon
References
J Cyst Fibros. 2019 Jun 5. pii: S1569-1993(19)30774-X. doi: 10.1016/j.jcf.2019.05.020.
Keywords
Biomarkers, Proteomics, Pulmonary exacerbations
PDF icon JCF-D-19-00159R1_FINAL_Quon_050819.pdf
Scientific Abstract
Title: Abnormal Pro-Gly-Pro pathway and airway neutrophilia in pediatric cystic fibrosis
Authors
Turnbull AR, Pyle CJ, Patel DF, Jackson PL, Hilliard TN, Regamey N, Tan HL, Brown S, Thursfield R, Short C, Mc Fie M, Alton EWFW, Gaggar A, Blalock JE, Lloyd CM, Bush A, Davies JC, Snelgrove RJ
References
J Cyst Fibros. 2019 Jun 5. pii: S1569-1993(19)30769-6. doi: 10.1016/j.jcf.2019.05.017
Keywords
matrikine, Neutrophil, protease
PDF icon CF Research News Article
Scientific Abstract