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Home > The combination elexacaftor/tezacaftor/ivacaftor (eti) alters the lipid composition of the lung cells irrespective of CFTR mutation

The combination elexacaftor/tezacaftor/ivacaftor (eti) alters the lipid composition of the lung cells irrespective of CFTR mutation

Resource Type

CF Research News

Authors

Nara Liessi, Valeria Tomati, Valeria Capurro, Nicoletta Loberto, Mar Garcia-Aloy, Pietro Franceschi, Massimo Aureli, Nicoletta Pedemonte, Andrea Armirotti

References

J Cyst Fibros. 2023 Apr 21;S1569-1993(23)00115-7. doi: 10.1016/j.jcf.2023.04.012.

Document

PDF icon CF Research News Article [1]

Link

Scientific Abstract [2]

Theme

CFTR/Basic Science [3]

Keywords

dihydroceramides [4]
lipidomics [5]
off-target effect [6]
sphingolipids [7]
triple combination ETI [8]

Date

Friday, April 21, 2023

Featured resource article

Yes

Resource - Guideline Type

Other Guidelines [9]
Source URL:https://www.ecfs.eu/resource-article/cf-research-news/combination-elexacaftortezacaftorivacaftor-eti-alters-lipid

Links
[1] https://www.ecfs.eu/sites/default/files/cf-research-article-files/JCF-D-23-00094R1_FINAL_Armirotti_040623.pdf [2] https://pubmed.ncbi.nlm.nih.gov/37088636/ [3] https://www.ecfs.eu/research-article-themes/cftrbasic-science [4] https://www.ecfs.eu/research-article-keywords/dihydroceramides [5] https://www.ecfs.eu/research-article-keywords/lipidomics [6] https://www.ecfs.eu/research-article-keywords/target-effect [7] https://www.ecfs.eu/research-article-keywords/sphingolipids [8] https://www.ecfs.eu/research-article-keywords/triple-combination-eti [9] https://www.ecfs.eu/resource-guideline-type/other-guidelines