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Home > Targeting G542X CFTR Nonsense Alleles With ELX-02 Restores CFTR Function in Human-Derived Intestinal Organoids

Targeting G542X CFTR Nonsense Alleles With ELX-02 Restores CFTR Function in Human-Derived Intestinal Organoids

Resource Type

CF Research News

Authors

Daniel K Crawford, Jasper Mullenders, Johanna Pott, Sylvia F Boj, Shira Landskroner-Eiger, Matthew M Goddeeris

References

J Cyst Fibros. 2021 Feb 5;S1569-1993(21)00028-X. doi: 10.1016/j.jcf.2021.01.009.

Document

PDF icon CF Research News Article [1]

Link

Scientific Abstract [2]

Keywords

ELX-02 [3]
NB124 [4]
Nonsense allele [5]
Organoid [6]
Read-through [7]

Date

Friday, February 5, 2021

Featured resource article

Yes

Resource - Guideline Type

Other Guidelines [8]
Source URL:https://www.ecfs.eu/resource-article/cf-research-news/targeting-g542x-cftr-nonsense-alleles-elx-02-restores-cftr

Links
[1] https://www.ecfs.eu/sites/default/files/cf-research-article-files/JCF-D-20-00485R1_FINAL_Goddeeris_110321.pdf [2] https://pubmed.ncbi.nlm.nih.gov/33558100/ [3] https://www.ecfs.eu/research-article-keywords/elx-02 [4] https://www.ecfs.eu/research-article-keywords/nb124 [5] https://www.ecfs.eu/research-article-keywords/nonsense-allele [6] https://www.ecfs.eu/research-article-keywords/organoid [7] https://www.ecfs.eu/research-article-keywords/read-through [8] https://www.ecfs.eu/resource-guideline-type/other-guidelines