Published on European Cystic Fibrosis Society (ECFS) (https://www.ecfs.eu)

Home > Emerging preclinical modulators developed for F508del-CFTR have the potential to be effective for ORKAMBI resistant processing mutants

Emerging preclinical modulators developed for F508del-CFTR have the potential to be effective for ORKAMBI resistant processing mutants

Resource Type

CF Research News

Authors

Onofrio Laselva, Claire Bartlett, Alec Popa, Hong Ouyang, Tarini N A Gunawardena, Tanja Gonska, Theo J Moraes, Christine E Bear

References

J Cyst Fibros. 2021 Jan;20(1):106-119. doi: 10.1016/j.jcf.2020.07.015. Epub 2020 Jul 30.

Document

PDF icon CF Research News Article [1]

Link

Scientific Abstract [2]

Keywords

CFTR [3]
Patient-derived nasal epithelial cultures [4]
Personalised medicine [5]
Rare mutations [6]

Date

Wednesday, January 20, 2021

Featured resource article

Yes

Resource - Guideline Type

Other Guidelines [7]
Source URL:https://www.ecfs.eu/resource-article/cf-research-news/emerging-preclinical-modulators-developed-f508del-cftr-have

Links
[1] https://www.ecfs.eu/sites/default/files/cf-research-article-files/JCF-D-20_00083R3_FINAL_Bear_250221.pdf [2] https://pubmed.ncbi.nlm.nih.gov/32741662/ [3] https://www.ecfs.eu/research-article-keywords/cftr [4] https://www.ecfs.eu/research-article-keywords/patient-derived-nasal-epithelial-cultures [5] https://www.ecfs.eu/research-article-keywords/personalised-medicine [6] https://www.ecfs.eu/research-article-keywords/rare-mutations [7] https://www.ecfs.eu/resource-guideline-type/other-guidelines