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Home > Decreased mRNA and protein stability of W1282X limits response to modulator therapy

Decreased mRNA and protein stability of W1282X limits response to modulator therapy

Resource Type

CF Research News

Authors

Aksit MA, Bowling AD, Evans TA, Joynt AT, Osorio D, Patel S, West N, Merlo C, Sosnay PR, Cutting GR, Sharma N

References

J Cyst Fibros. 2019 Sep;18(5):606-613. doi: 10.1016/j.jcf.2019.02.009. Epub 2019 Feb 23.

Document

PDF icon CF Research News Article [1]

Link

Scientific Abstract [2]

Date

Wednesday, September 18, 2019

Featured resource article

Yes

Resource - Guideline Type

Other Guidelines [3]
Source URL:https://www.ecfs.eu/resource-article/cf-research-news/decreased-mrna-and-protein-stability-w1282x-limits-response

Links
[1] https://www.ecfs.eu/sites/default/files/cf-research-article-files/JCF-D-18-00338R2_FINAL_Sharma_301019.pdf [2] https://www.ncbi.nlm.nih.gov/pubmed/?term=DECREASED%20MRNA%20AND%20PROTEIN%20STABILITY%20OF%20W1282X%20LIMITS%20RESPONSE%20TO%20MODULATOR%20THERAPY [3] https://www.ecfs.eu/resource-guideline-type/other-guidelines