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Home > Pharmacokinetics and safety of cavosonstat (N91115) in healthy and cystic fibrosis adults homozygous for F508DEL-CFTR

Pharmacokinetics and safety of cavosonstat (N91115) in healthy and cystic fibrosis adults homozygous for F508DEL-CFTR

Resource Type

CF Research News

Authors

Scott H. Donaldson, George M. Solomon, Pamela L. Zeitlin, Patrick A. Flume, Alicia Casey, Karen McCoy, Edith T. Zemanick, Arun Mandagere, Janice M. Troha, Steven A. Shoemaker, James F. Chmiel, Jennifer L. Taylor-Cousar

References

J Cyst Fibros. 2017 May;16(3):371-379. doi: 10.1016/j.jcf.2017.01.009. Epub 2017 Feb 13.

Document

PDF icon CF Research News Article [1]

Link

Scientific Abstract [2]

Keywords

CFTR stabilizer [3]
GSNOR [4]
F508del-CFTR [5]
Homozygous [6]
Modulator [7]

Date

Tuesday, May 16, 2017

Featured resource article

Yes

Resource - Guideline Type

Other Guidelines [8]
Source URL:https://www.ecfs.eu/resource-article/cf-research-news/pharmacokinetics-and-safety-cavosonstat-n91115-healthy-and-cystic

Links
[1] https://www.ecfs.eu/sites/default/files/cf-research-article-files/JCF-D-16-00313R2_Final_Donaldson_20022017.pdf [2] https://www.ncbi.nlm.nih.gov/pubmed/?term=Pharmacokinetics%20and%20safety%20of%20cavosonstat%20%28N91115%29%20in%20healthy%20and%20cystic%20fibrosis%20adults%20homozygous%20for%20F508DEL-CFTR [3] https://www.ecfs.eu/research-article-keywords/cftr-stabilizer [4] https://www.ecfs.eu/research-article-keywords/gsnor [5] https://www.ecfs.eu/research-article-keywords/f508del-cftr [6] https://www.ecfs.eu/research-article-keywords/homozygous [7] https://www.ecfs.eu/research-article-keywords/modulator [8] https://www.ecfs.eu/resource-guideline-type/other-guidelines