Published on European Cystic Fibrosis Society (ECFS) (https://www.ecfs.eu)

Home > A small molecule neutrophil elastase inhibitor, KRP-109, inhibits cystic fibrosis mucin degradation

A small molecule neutrophil elastase inhibitor, KRP-109, inhibits cystic fibrosis mucin degradation

Resource Type

CF Research News

Authors

Shashi Chillappagari
Christian Müller
Poornima Mahavadi
Andreas Guenther
Lutz Nährlich
Jonathan Rosenblum
Bruce K. Rubin
Markus O.Henke

References

J Cyst Fibros. 2015 Oct 29. pii: S1569-1993(15)00250-7

Document

PDF icon CF Research News article [1]

Link

Scientific abstract [2]

Keywords

Protease and anti-protease balance [3]
Small molecule inhibitors [4]

Date

Thursday, October 1, 2015

Featured resource article

No
Source URL:https://www.ecfs.eu/content/small-molecule-neutrophil-elastase-inhibitor-krp-109-inhibits-cystic-fibrosis-mucin

Links
[1] https://www.ecfs.eu/sites/default/files/cf-research-article-files/JCF-D-15-00204R1_FINAL_Henke_06022016.pdf [2] http://www.ncbi.nlm.nih.gov/pubmed/?term=A%20small%20molecule%20neutrophil%20elastase%20inhibitor%2C%20KRP-109%2C%20inhibits%20cystic%20fibrosis%20mucin%20degradation [3] https://www.ecfs.eu/research-article-keywords/protease-and-anti-protease-balance [4] https://www.ecfs.eu/research-article-keywords/small-molecule-inhibitors