European Cystic Fibrosis Society

Trials in CTN sites

Updated 16 May 2012

Introduction:

Here you can find an overview of clinical trials that are ongoing in hospitals that are part of the  ECFS Clinical Trials Network (CTN). For studies that are finished, the study results are posted as soon as they are available.

Here you find the full list of  European CF centers making out the network.

Studies only run in CTN sites after a formal review of the study protocol and approval by a committee of experts. This does not mean that all CTN centers will participate in a specific study. Each study overview sheet will list the participating CTN sites.  Some CTN approved studies also run in additional centers that are not part of the CTN network. A complete list of participating sites can be found on the specific www.clinicaltrials.gov (external link) that is mentioned for each study  overview sheet.

In case you want to participate in some of the trials listed here, please consult your treating physician/doctor.  The overview lists the studies under: "recruitment started" or under “recruitment finished”.  In addition, the studies are categorized according to the drug’s mechanism of action:

• CFTR modulation
• Restore Airway Surface Liquid
• Mucus alteration
• Anti-inflammatory
• Anti-infective (Antibiotics)
• Bronchodilatators
• Nutrition

The ECFS-CTN cannot guarantee that the information provided here is completely comprehensive. Please go to the ClinicalTrials.gov link for detailed and up to date information on study background, eligibility criteria, study design, outcome measures, study status, participating sites, sponsor contact information and timelines.

You can also contact the CTN coordinating centre for additional information:
ECFS-CTN@uzleuven.be

Overview of Studies

Recruitment Started

          - Novartis EARLY study (Tobi in children)
          - Mukoviszidose Institut gGmbH: Efficacy Study of IgY (Antibody Against Pseudomonas) in
            Cystic Fibrosis Patients (PsAer-IgY)

          - TORPEDO-CF
          - Insmed Arikace TR02-108
          - Gilead GS-US-205-0162 "Alpine"
          - Gilead GS-US-205-0160 "PALS"

Recruitment Completed

              - GSK CF2110399

    • Bronchodilatators 

              - Boehringer Tiotropium Phase 2 - includes Study Results (in PDF)

    - Boehringer Tiotropium Phase 3